Sterols lower energetic barriers of membrane bending and fission necessary for efficient clathrin mediated endocytosis
R. H. Anderson, K. L. Sochacki, H. Vuppula, B. L. Scott, E. M. Bailey, M. M. Schultz, J. G. Kerkvliet, J. W. Taraska, A. D. Hoppe, K. R. Francis
This study shows that sterols reduce the energy required for membrane bending and fission during clathrin-mediated endocytosis, and that their depletion impairs this process and affects cellular function.
bioRxiv · Jan 31, 2021Cell Biology