Neuronal Hyperactivity in Neurons Derived from Individuals with Grey Matter Heterotopia
Francesco Di Matteo, Rebecca Bonrath, Hanna Schmidt, Ane Cristina Ayo Martin, Veronica M. Pravatà, Rossella Di Giaimo, Danusa Menegaz, Stephan Riesenberg, Femke M. S. de Vrij, Giuseppina Maccarrone, Maria Holzapfel, Tobias Straub, Steven A. Kushner, Stephen P. Robertson, Matthias Eder, Silvia Cappello
This study investigates neuronal hyperactivity in human cerebral organoids derived from individuals with grey matter heterotopia, identifying functional and structural changes linked to the condition.
bioRxiv · Jul 10, 2024 · PreprintNeuroscience