Mapping adaptive immune responses toward fungal antigens in inflammatory bowel disease using T cell repertoire sequencing and phage-immunoprecipitation sequencing
Aya K.H. Mahdy, Hesham ElAbd, Melanie Prinzensteiner, Hannah Jebens, Kostas Sivickis, Petra Bächer, Thomas J. Vogl, Mathilde Poyet, André Franke
This study maps immune responses to fungal antigens in IBD using T cell repertoire sequencing and PhIP-Seq, identifying T cell clonotypes and antibody responses against S. cerevisiae proteins.
Journal of Crohn s and Colitis · Jan 31, 2026Peer-reviewedImmunology