Author

Hao Zhou

Brigham and Women's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Microbiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:diffusion model· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:ecology & biodiversity· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ake Tzu-Hui LuiD· 1 shared Alexander TyshkovskiyiD· 1 shared Amin HaghaniiD· 1 shared Chaofang Zhong· 1 shared Chaoyun CheniD· 1 shared Chunyu Zhou· 1 shared Duanhua CaoiD· 1 shared Friederike MartiniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperSystems Biology

Ake Tzu-Hui LuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Transplanted hearts assimilate the recipient's biological age

Jesse R. Poganik, Tomohisa Matsunaga, Alexander Tyshkovskiy, Ake Tzu-Hui Lu, Amin Haghani, Hao Zhou, Friederike Martin, Steve Horvath, Michael M. Givertz, Stefan G. Tullius, Vadim N. Gladyshev

DNA methylation clocks show heterochronic heart grafts shifting toward recipient age in syngeneic mice and 11 human recipients, while recipient mouse native heart, liver and blood show no consistent change.

bioRxiv · Sep 17, 2026 · PreprintSystems Biology✦ In-depth digest

SurfDock is a Surface-Informed Diffusion Generative Model for Reliable and Accurate Protein-ligand Complex Prediction

Duanhua Cao, Mingan Chen, Runze Zhang, Zhaokun Wang, Manlin Huang, Jie Yu, Xinyu Jiang, Zhehuan Fan, Wei Zhang, Hao Zhou, Xutong Li, Zunyun Fu, Sulin Zhang, Mingyue Zheng

SurfDock improves protein-ligand complex prediction by integrating multiple protein representations into a diffusion model, achieving higher accuracy and physical plausibility than existing methods.

Nature Methods · Nov 27, 2024Peer-reviewedBioinformatics

Agricultural Pollution Risks Influence Microbial Ecology in Honghu Lake

Maozhen Han, Melissa Dsouza, Chunyu Zhou, Hongjun Li, Junqian Zhang, Chaoyun Chen, Qi Yao, Chaofang Zhong, Hao Zhou, Jack A Gilbert, Zhi Wang, Kang Ning

This study examines how agricultural pollution affects microbial communities in Honghu Lake, finding that physicochemical and antibiotic factors drive changes in microbial diversity and structure.

bioRxiv · Jan 8, 2018 · PreprintMicrobiology