Targeted tumor desialylation by engineered probiotic reprograms the tumor microenvironment to potentiate immunotherapy
Jinhui Wang, Jing Wang, Tao OuYang, Bin Shi, He Meng, Zong‐Wan Mao, Wei Ting Xia
This paper engineers a probiotic to desialylate tumors, enhancing immunotherapy efficacy by reprogramming the tumor microenvironment.
bioRxiv · Oct 6, 2026 · PreprintSynthetic Biology