Author

Herbert Castillo

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Microbiology· 1

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Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1 Research Focus:phylogenetics / evolution· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Brian R. CraneiD· 1 shared Igor B. ZhuliniD· 1 shared Jiawei XingiD· 1 shared Maithili DeshpandeiD· 1 shared Robert DunleavyiD· 1 shared Vadim M. GumeroviD· 1 shared

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2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

Brian R. CraneORCID

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1 paper

Recent·Most cited

A dichotomous family of Cache domain proteins evolved through c-type heme acquisition

Maithili Deshpande, Jiawei Xing, Vadim M. Gumerov, Robert Dunleavy, Herbert Castillo, Brian R. Crane, Igor B. Zhulin

Cache sensor domains of DUF3365/Tll0287 family bind covalent c-type heme through a CXXCH insertion; a signaling member behaves like an NO sensor, a stand-alone one like a redox protein.

bioRxiv · Oct 1, 2026 · PreprintMicrobiology✦ In-depth digest