Burden of rare pathogenic variants suggests disrupted cytoskeletal organisation in the pathogenesis of pulmonary fibrosis
Konain Bhatti, Dapeng Wang, Hernan Fainberg, Andressa Alves Bordignon, Yujie Ni, Bin Liu, Simon R. Johnson, Richard Allen, Louise V. Wain, Toby M. Maher, Philip L Molyneaux, Elisabetta Renzoni, Gauri Saini, Deborah Morris-Rosendahl, Gisli R. Jenkins, Iain D. Stewart
The paper identifies rare pathogenic variants associated with pulmonary fibrosis by analyzing whole genome sequencing data and linking them to cytoskeletal dysfunction.
bioRxiv · Jun 10, 2024 · PreprintGenetics