Reversible Opto-Chemical activation of KRASG12V signaling with near single-cell precision
Luis Manuel Muñoz-Nava, Maria Bespalova, Mario O. Caracci, Kitso Ata Kewagamang, Birga Soetje, Sabrina Seidler, Kirsten Michel, Holger Vogel, Janicke Maerz, Philippe I. H. Bastiaens
This paper develops a reversible Opto-Chemical system to activate KRASG12V signaling with near single-cell precision and demonstrates its effects on epithelial transformation.
bioRxiv · Jul 7, 2026 · PreprintSystems Biology