Author

Holly Steach

Arsenal Biosciences (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Aaron R. CooperiD· 1 shared Adam Barner· 1 shared Allyson J. MerrelliD· 1 shared Amaro N Taylor-WeineriD· 1 shared Andrea Fua· 1 shared Andrew Cardozo· 1 shared Angela C. BoroughsiD· 1 shared Ankim Nguyen· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Aaron R. CooperORCID

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1 paper

Recent·Most cited

DINOcell: Learning Generalizable Perturbation Effects through Self-Distillation

Jonathan Li, Nilgun Tasdemir, Sofia Kyriazopoulou-Panagiotopoulou, Sophie Xu, Allyson J. Merrell, Josephine Susanto, Ashley A. Cass, David DeTomaso, Holly Steach, Julie C. Chow, Li Wang, Neal G. Ravindra, Aram Kang, Grace X. Y. Zheng, Mary Chua, , Amaro N Taylor-Weiner

DINOcell predicts cellular responses to perturbations using self-distillation in single-cell transcriptomics, outperforming baselines for single and combination gene effects.

bioRxiv · Dec 19, 2025 · PreprintBioinformatics