Peripheral alcohol metabolism dictates ethanol consumption and drinking microstructure in mice
Bryan Mackowiak, David L. Haggerty, Taylor Lehner, Yu‐Hong Lin, Yaojie Fu, Hongkun Lu, Robert J. Pawlosky, Tianyi Ren, Wonhyo Seo, Dechun Feng, Li Zhang, David M. Lovinger, Bin Gao
This study shows that ADH1-mediated ethanol metabolism affects ethanol consumption and drinking patterns in mice, with Adh1 KO and inhibitor treatments reducing consumption and altering drinking microstructure.
Alcoholism Clinical and Experimental Research · Mar 21, 2025Peer-reviewedNeuroscience