Author

Hui Guo

First Affiliated Hospital of Kunming Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genetics· 2 Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:fine-mapping· 2 Assay:GWAS summary statistics· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Chris WallaceiD· 2 shared Maria Ban· 2 shared Neil M WalkeriD· 2 shared Anne Barton· 1 shared Antony J Cutler· 1 shared Arcadio Rubio Garcia· 1 shared Deborah J Smyth· 1 shared Ellen Schofield· 1 shared

Activity by Year

2015-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersGenetics

Chris WallaceORCID

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Author profile →

4 papers

Recent·Most cited

Production and functional verification of 8-gene (GGTA1, CMAH, β4GalNT2, hCD46, hCD55, hCD59, hTBM, hCD39)-edited donor pigs for xenotransplantation

Jiaoxiang Wang, Kaixiang Xu, Tao Liu, Heng Zhao, Muhammad Ameen Jamal, Gen Chen, Xiaoying Huo, YANG Chang, JIAO Deling, WEI Taiyun, HanFei Huang, Zhao hongfang, Guo JianXiong, Fengchong Wang, Xiong Zhang, , Hongjiang Wei

The paper edits 8 genes in pigs to reduce immune rejection and tests their effectiveness in xenotransplantation to non-human primates.

Cell Proliferation · Apr 6, 2025Peer-reviewedGenetics

Attention-based GCN Integrates Multi-omics Data for Breast Cancer Subtype Classification and Patient-specific Gene Marker Identification

Hui Guo, Xiang Lv, Yizhou Li, Menglong Li

This paper introduces an attention-based GCN method for breast cancer subtype classification using multi-omics data and identifies patient-specific gene markers through interpretability techniques.

Briefings in Functional Genomics · Mar 28, 2023Peer-reviewedBioinformatics

Dissection of a complex disease susceptibility region using a Bayesian stochastic search approach to fine mapping

Chris Wallace, Antony J Cutler, Nikolas Pontikos, Marcin L Pekalski, Oliver S Burren, Jason D Cooper, Arcadio Rubio Garcia, Ricardo C Ferreira, Hui Guo, Neil M Walker, Deborah J Smyth, Stephen S Rich, Suna Onengut-Gumuscu, Stephen S Sawcer, Maria Ban, , Linda Wicker

This study uses a Bayesian stochastic search method to fine map genetic variants in the IL-2RA region associated with multiple sclerosis and type 1 diabetes, identifying shared causal variants.

PLOS Genetics · Jun 24, 2015Peer-reviewedGenetics

Statistical Colocalization of Genetic Risk Variants for Related Autoimmune Diseases in the Context of Common Controls

Mary D Fortune, Hui Guo, Oliver Burren, Ellen Schofield, Neil M Walker, Maria Ban, Stephen J Sawcer, John Bowes, Jane Worthington, Anne Barton, Steve Eyre, John A Todd, Chris Wallace

The paper identifies shared and distinct genetic risk variants across four autoimmune diseases using colocalization methods with shared control data, revealing novel associations and complex patterns.

Nature Genetics · Jun 8, 2015Peer-reviewedGenomics