Author

Huihui Xu

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Amjad HoraniiD· 3 shared Ahmed Elgamal· 2 shared Nicholas Hadas· 2 shared Shambhawee Neupane· 2 shared Wang Kyaw TwaniD· 2 shared Andrew C. BericaliD· 1 shared Anjali JacobiD· 1 shared Daniel J. WallmaniD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

Amjad HoraniORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Comparative Single-Cell Transcriptomics Uncovers Shared and Distinct Molecular Signatures in Cystic Fibrosis and Primary Ciliary Dyskinesia

Nicholas Hadas, Huihui Xu, Wang Kyaw Twan, Shambhawee Neupane, Ahmed Elgamal, Jeffrey R. Koenitzer, Amjad Horani

This study compares single-cell transcriptomes of Cystic Fibrosis and Primary Ciliary Dyskinesia to identify distinct molecular signatures and pathways.

bioRxiv · Nov 17, 2025 · PreprintCell Biology

Machine Learning Analysis of Cilia-Driven Particle Transport Distinguishes Primary Ciliary Dyskinesia Cilia from Normal Cilia

Nicholas Hadas, Huihui Xu, Shambhawee Neupane, Wang Kyaw Twan, Ahmed Elgamal, Amjad Horani

The paper uses machine learning to analyze cilia-driven particle transport and distinguishes PCD cilia from normal cilia with high accuracy.

bioRxiv · Nov 2, 2025 · PreprintBioinformatics

A stem cell-based platform for functional analysis of genetic variants in lung disease

Daniel J. Wallman, Sachiko T. Homma, Madeleine Finton, M.L Beermann, Anjali Jacob, Semil P. Choksi, Steven D. Pletcher, Huihui Xu, Pushpinder Bawa, Jeremy F. Reiter, Amjad Horani, Steven L. Brody, Andrew C. Berical, Finn J Hawkins

This study develops an iPSC-based platform to functionally analyze genetic variants in lung disease, demonstrating its application in diagnosing a variant of uncertain significance in primary ciliary dyskinesia.

bioRxiv · Jul 28, 2025 · PreprintCell Biology