Author

Huiling Zhang

South China Agricultural University

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Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:contrastive learning· 1 Approach:deep learning· 1 Organism:human· 1 Assay:protein sequence· 1 Approach:transformer / foundation model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Ganzhang Zheng· 1 shared Haowen Zhao· 1 shared Shaozhen Cai· 1 shared Yanjie WeiiD· 1 shared Yuxiang Huang· 1 shared Zihan ZhouiD· 1 shared Ziqi XuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Ganzhang Zheng

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1 paper

Recent·Most cited

VarDCL: A Multimodal PLM-Enhanced Framework for Missense Variant Effect Prediction via Self-distilled Contrastive Learning

Huiling Zhang, Ganzhang Zheng, Ziqi Xu, Haowen Zhao, Shaozhen Cai, Yuxiang Huang, Zihan Zhou, Yanjie Wei

VarDCL predicts pathogenic missense variants by integrating multimodal protein language model embeddings and self-distilled contrastive learning, achieving high performance on clinical variants.

bioRxiv · Mar 17, 2026 · PreprintBioinformatics