Author

Yuxiang Huang

South China Agricultural UniversityPrimary ORCID profile (0009-0005-5505-3526 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Yuxiang HuangiD1 paper · University of Michigan

Biology Disciplines

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Bioinformatics· 1

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Approach:contrastive learning· 1 Approach:deep learning· 1 Organism:human· 1 Assay:protein sequence· 1 Approach:transformer / foundation model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Ganzhang Zheng· 1 shared Haowen Zhao· 1 shared Huiling Zhang· 1 shared Shaozhen Cai· 1 shared Yanjie WeiiD· 1 shared Zihan ZhouiD· 1 shared Ziqi XuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Ganzhang Zheng

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintMar 17, 2026

VarDCL: A Multimodal PLM-Enhanced Framework for Missense Variant Effect Prediction via Self-distilled Contrastive Learning

Huiling Zhang, Ganzhang Zheng, Ziqi Xu…·Yanjie Wei

VarDCL predicts pathogenic missense variants by integrating multimodal protein language model embeddings and self-distilled contrastive learning, achieving high performance on clinical variants.

DOI 10.64898/2026.03.13.711612

humanprotein sequence

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