Oxytocin facilitates social behavior of female rats via selective modulation of interneurons in the medial prefrontal cortex
Stephanie Schimmer, Alan Kania, Arthur Lefèvre, Konstantinos Afordakos, Kai-Yi Wang, Julia Lebedeva, Andrei V. Rozov, Androniki Raftogianni, Rishika Tiwari, Shai Netser, Ana Zovko, Huma Shaheen, Jonas Schimmer, Ryan Patwell, Clémence Denis, , Valery Grinevich
This study identifies a circuit in the medial prefrontal cortex where oxytocin modulates interneurons to promote social behavior in female rats, even under physiological stress.
Nature Communications · Feb 20, 2026Peer-reviewedNeuroscience