Mapping the regulatory wiring of endothelial cell differentiation reveals a critical role for Hippo mechanosignaling
Tri C. Nguyen, Hunter D. King, Dulguun Amgalan, Olga Pushkarev, Yanyan Alexandra Mo, Chad J. Munger, Chloe McCreery, Revant Gupta, Tony Zeng, Ronghao Zhou, Stephanie D. Conley, Surya Prakash Rao Batta, Maya U. Sheth, Eugenio Mattei, Anastasiia Masaltseva, , Jesse M. Engreitz
The paper maps gene regulators of endothelial cell differentiation using CRISPR and single-cell RNA-seq, identifying Hippo mechanosignaling as critical for endothelial identity.
bioRxiv · Nov 5, 2026 · PreprintGenomics