Author

I. Abdi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

L. M. Berger· 3 shared R. Tesch· 3 shared S. Knapp· 3 shared T. Hanke· 3 shared A. C. Joerger· 2 shared A. Poso· 2 shared B.-T. Berger· 2 shared M. Rak· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiochemistry

L. M. Berger

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Development of selective pyridopyrimidin-7(8H)-one-based Mammalian STE20-like (MST3/4) kinase inhibitors

M. Rak, A. Menge, R. Tesch, L. M. Berger, D.-I. Balourdas, E. Shevchenko, A. Kraemer, L. Elson, B.-T. Berger, I. Abdi, L. M. Wahl, A. Poso, A. Kaiser, T. Hanke, T. Kronenberger, , S. Knapp

This study develops selective MST3/4 kinase inhibitors and demonstrates their distinct cellular effects compared to MST1/2 inhibition.

bioRxiv · Nov 24, 2023Biochemistry

Self-Assembly of a Repeatable DNA Nanohinge System Supporting Higher Order Structure Formation

M. Law, C. Sushams, D. Mackay, S. Nguyen, R. Nicholas, M. R. G. Tsai, E. Rajkumar, F. Inaba, K. Maheden, I. Abdi, J. C. H. Ho, B. Kieft, S. J. Hallam

This paper introduces a repeatable DNA nanohinge system that improves scalability and functionality for higher order structure formation in DNA nanostructures.

bioRxiv · May 26, 2023 · PreprintBioengineering

Structure-based design of selective salt-inducible kinase (SIK) inhibitors

R. Tesch, M. Rak, M. Raab, L. M. Berger, T. Kronenberger, A. C. Joerger, B. T. Berger, I. Abdi, T. Hanke, A. Poso, K. Strebhardt, M. Sanhaji, S. Knapp

This study designs a selective SIK inhibitor, MRIA9, based on a PAK inhibitor, showing its dual activity and potential for combination therapy in ovarian cancer.

bioRxiv · Apr 8, 2021 · PreprintBiochemistry

A Highly Selective Chemical Probe for Activin Receptor-like Kinases ALK4 and ALK5

T. Hanke, J. F. Wong, B.-T. Berger, I. Abdi, L. M. Berger, R. Tesch, C. Tredup, A. N. Bullock, S. Mueller, S. Knapp

The paper develops a selective chemical probe, TP-008, for ALK4 and ALK5 kinases and provides a negative control, enabling mechanistic studies of their signaling pathway and disease roles.

bioRxiv · Jan 23, 2020Biochemistry