Lipid Droplets and Ferritin Heavy Chain: a Devilish Liaison in Cancer Radioresistance
L. Tirinato, M. G. Marafioti, F. Pagliari, J. Jansen, I. Aversa, R. Hanley, C. Nistico, D. Garcia-Calderon, G. Genard, J. F. Guerreiro, F. S. Costanzo, J. Seco
The paper identifies a novel mechanism linking lipid droplets and ferritin heavy chain in cancer radioresistance, showing that FTH1 promotes radioresistance through LD accumulation.
bioRxiv · May 11, 2021Cancer Biology