SARS-CoV-2 escapes CD8 T cell surveillance via mutations in MHC-I restricted epitopes
B. Agerer, M. Koblischke, V. Gudipati, M. Smyth, A. Popa, J.-W. Genger, L. Endler, D. M. Florian, V. Muehlgrabner, A. Lercher, P. Gattinger, R. Torralba-Gombau, T. Penz, I. Fae, S. Wenda, , A. Bergthaler
The paper identifies mutations in SARS-CoV-2 that reduce MHC-I binding and CD8+ T cell recognition, suggesting escape from immune surveillance.
bioRxiv · Dec 18, 2020 · PreprintImmunology