The human vault RNA enhances tumorigenesis and chemoresistance through the lysosome
I. Ferro, J. Gavini, L. Bracher, M. Landolfo, D. Candinas, D. Stroka, N. Polacek
This study shows that vtRNA1-1 promotes tumorigenesis and chemoresistance by regulating lysosomal function through the ERK1/2-TFEB pathway.
bioRxiv · Jun 28, 2020Cell Biology