Pharmacological inhibition of titan-like cells formation suggests that accumulation of endogenous free radicals that correlate with mitochondrial changes are required to induce this transition in Cryptococcus neoformans
I. Garcia-Barbazan, R. Garcia-Rodas, M. Sachse, D. Luque, D. Megias, O. Zaragoza
This paper identifies compounds that inhibit titan-like cell formation in Cryptococcus neoformans, suggesting that endogenous ROS and mitochondrial changes are critical for this process.
bioRxiv · Apr 6, 2022 · PreprintMicrobiology