Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the global transcriptional regulator Lsr2
K. Alqaseer, O. Turapov, P. Barthe, H. Jagatia, A. d. Visch, C. Roumestand, M. Wegrzyn, I. L. Bartek, M. I. Voskuil, H. O'Hare, A. A. Witney, M. Cohen-Gonsaud, S. J. Waddell, G. V. Mukamolova
This study shows that PknB phosphorylates Lsr2, affecting its DNA binding and M. tuberculosis growth under hypoxia.
bioRxiv · Mar 8, 2019Microbiology