Water-mediated interactions enable smooth substrate transport in a bacterial efflux pump
A. V. Vargiu, V. K. Ramaswamy, I. Malvacio, G. Malloci, U. Kleinekatöfer, P. Ruggerone
The paper investigates the role of water-mediated interactions in the substrate transport mechanism of the bacterial efflux pump AcrB, revealing how structured waters facilitate substrate diffusion.
bioRxiv · Aug 30, 2017Biophysics