Phylogenetic profiling suggests early origin of the core subunits of Polycomb Repressive Complex 2 (PRC2)
A. Sharaf, M. Vijayanathan, M. Obornik, i. Mozgova
The paper uses phylogenetic analysis to show that PRC2 core subunits originated in early eukaryotic lineages, with E(z) and ESC present in the conserved core and Su(z)12 possibly emerging later.
bioRxiv · Jul 16, 2021 · PreprintEvolutionary Biology