Structural basis of nanobody-recognition of grapevine fanleaf virus and of virus resistance loss
I. Orlov, C. Hemmer, L. Ackerer, B. Lorber, A. Ghannam, V. Poignavent, K. Hleibieh, C. Sauter, C. Schmitt-Keichinger, L. Belval, J.-M. Hily, A. Marmonier, V. Komar, S. Gersch, P. Schellenberger, , B. Klaholz
The paper presents the cryo-EM structure of the GFLV-Nb23 complex, revealing the molecular recognition mechanism and resistance-breaking variants of GFLV.
bioRxiv · Aug 8, 2019Biochemistry