Quantum pBac: An effective, high-capacity piggyBac-based gene integration vector system for unlocking gene therapy potential
W.-K. Hua, J. C. Hsu, Y.-C. Chen, P. S. Chang, K.-L. K. Wen, P.-N. Wang, Y.-S. Yu, Y.-C. Chen, I.-C. Cheng, S. C.-Y. Wu
This paper develops a virus-free gene therapy vector system, Quantum pBac, which improves transposition efficiency and payload capacity for CAR-T cell production.
bioRxiv · Apr 29, 2022Cancer Biology