Author

Iris-Sofia Bibli

Heidelberg University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Carolin LerchenmülleriD· 2 shared Daniel DuerschmiediD· 2 shared Harald F. LangeriD· 2 shared Hellmut G. AugustiniD· 2 shared Henry NordingiD· 2 shared Jacob von EsebeckiD· 2 shared Jens Uwe MarquardtiD· 2 shared Lara Hagemann· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Carolin LerchenmüllerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Platelet C5aR1 mediates sex-specific ischemia-driven revascularization through estradiol-dependent CXCL4 release

Henry Nording, Lasse Baron, Manuela Sauter, Lara Hagemann, Jacob von Esebeck, Nicolas Schommer, Daniel Duerschmied, Jens Uwe Marquardt, Carolin Lerchenmüller, Christine S. Zuern, Iris-Sofia Bibli, Hellmut G. Augustin, Oliver J Mueller, Harald F. Langer

This study identifies a sex-specific mechanism where platelet C5aR1 mediates ischemia-driven revascularization through estradiol-dependent CXCL4 release, explaining sex differences in cardiovascular outcomes.

bioRxiv · Jun 27, 2026 · PreprintImmunology

Platelet C5aR1 Aggravates Myocardial Infarction through Platelet-Neutrophil Interactions and CXCL4-Dependent NET Release

Henry Nording, Lasse Baron, Manuela Sauter, Lara Hagemann, Jacob von Esebeck, Nicolas Schommer, Daniel Duerschmied, Jens Uwe Marquardt, Carolin Lerchenmüller, Christine Zürn, Iris-Sofia Bibli, Hellmut G. Augustin, J. Müller Oliver, Harald F. Langer

This study shows that platelet C5aR1 worsens myocardial infarction by promoting neutrophil activation and NET release, and that targeting it can reduce cardiac damage.

bioRxiv · Jun 18, 2026 · PreprintImmunology