Cellular responses to FGF1 are modulated by palmitoylation of the docking protein FRS2α
Seong J. An, Yoshihisa Suzuki, Jyotidarsini Mohanty, Francisco Tomé, Irit Lax, Joseph Schlessinger
This study shows that palmitoylation of FRS2α is essential for FGF1-induced signaling and cellular responses, including MAPK activation and neuronal differentiation.
Proceedings of the National Academy of Sciences · Apr 29, 2026Peer-reviewedBiochemistry