AP-2α and AP-2β cooperatively function in the craniofacial surface ectoderm to regulate chromatin and gene expression dynamics during facial development.
Eric Van Otterloo, Isaac Milanda, Hamish Pike, Jamie A Thompson, Hong Li, Kenneth L Jones, Trevor Williams
This study shows that AP-2α and AP-2β regulate chromatin and gene expression in the craniofacial surface ectoderm, affecting facial development and WNT signaling in mice.
eLife · Mar 25, 2022Peer-reviewedDevelopmental Biology