Author

Isabel Koehler

Medical University of South Carolina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander Y. MasloviD· 1 shared Amy C. ReesiD· 1 shared Brian Orr· 1 shared Christopher Bradley· 1 shared Christopher de Solis· 1 shared D Jones· 1 shared Danyelle M. TownsendiD· 1 shared David T Long· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexander Y. MaslovORCID

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Author profile →

1 paper

Recent·Most cited

Metallothionein loss in cancer cells contributes to increased mutations through defective DNA repair and metabolic imbalance

Mirna Mina-Abouda, Amy C. Rees, Della R. Evans, Evan D. Villamor, George Fullbright, Heather R. Ghent, Madison A. Clark, Wendy Y Zhang, Isabel Koehler, Isabella Berry, Sydney Oesch, Robert Hutchinson, Davide Delisi, Christopher de Solis, Alexander Y. Maslov, , Joe Ryan Delaney

This study shows that loss of metallothionein (MT) in cancer cells increases mutations by impairing DNA repair and causing metabolic imbalance.

bioRxiv · Aug 12, 2026 · PreprintCancer Biology