The impact of non-cardiomyocyte MYBPC3 expression on the development of hypertrophic cardiomyopathy
Nicolas G. Clavere, J Kim, Katie Letcher, Sejal Molakaseema, Kavisha Silva, Soumojit Pal, Jason R. Becker
This study investigates the role of MYBPC3 expression in non-cardiomyocytes in HCM development, finding that cardiomyocytes are the primary source of extracardiac MYBPC3 mRNA and the main cell type responsible for the disease.
bioRxiv · Apr 23, 2026 · PreprintGenetics