J. A. Bohnert

In-host evolution of classic to convergent Klebsiella pneumoniae sequence type 147 isolates and impact of associated capsular changes on different morphotypes

This study investigates in-host evolution of Klebsiella pneumoniae sequence type 147 isolates, revealing microevolution from classic to convergent pathotype through plasmid acquisition and capsular changes affecting virulence and morphology.

Temperatures above 37°C increase virulence of a convergent Klebsiella pneumoniae sequence type 307 strain

This study shows that temperatures above 37°C increase hypermucoviscosity and virulence in a convergent Klebsiella pneumoniae strain, potentially due to plasmid-encoded factors and temperature-dependent regulatory changes.

Multi-omics investigations uncover unique pathogenic markers in clinical Klebsiella pneumoniae that could be leveraged as novel antimicrobial targets

This study identifies unique pathogenic markers in Klebsiella pneumoniae through multi-omics analysis, suggesting potential novel antimicrobial targets.