Stress-dependent inhibition of cell polarity through unbalancing the GEF/GAP regulation of Cdc42
C. Salat-Canela, M. Carmona, R. Martin-Garcia, P. Perez, J. Ayte, E. Hidalgo
The paper shows that oxidative stress inhibits Cdc42 activity at cell poles via Sty1 kinase, leading to reduced cell polarity and elongated morphology in fission yeast.
Cell Reports · Nov 1, 2021Peer-reviewedCell Biology