Impact of Phosphorylation on the Physiological Form of Human alpha-Synuclein in Aqueous Solution
E. de Bruyn, A. E. Dorn, G. Rossetti, C. Fernandez, T. F. Outeiro, J. B. Schulz, P. Carloni
This study uses molecular simulations to investigate how phosphorylation at serine 129 affects the structure of human alpha-synuclein in aqueous solution, finding no significant impact on its conformational ensemble.
bioRxiv · Mar 10, 2023Biophysics