Phosphorylation of tyrosine 90 in SH3 domain is a new regulatory switch controlling Src kinase
L. Koudelkova, Z. Bruhova, M. Sztacho, V. Pavlik, D. Panek, J. Gemperle, J. Brabek, D. Rosel
This study identifies phosphorylation of tyrosine 90 in SH3 domain as a regulatory switch that activates Src kinase by altering its conformation and interactions.
bioRxiv · Aug 23, 2022Cell Biology