Author

J. Bruset

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Pharmacology & Toxicology· 1

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Approach:statistical model· 1

Frequent Co-Authors

A. Chaumot· 1 shared C. Lopes· 1 shared D. Lamonica· 1 shared O. Geffard· 1 shared O. Gestin· 1 shared S. Charles· 1 shared T. LACOUE-LABARTHE· 1 shared V. Baudrot· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Chaumot

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1 paper

Recent·Most cited

Generic solving of physiologically-based kinetic models in support of next generation risk assessment due to chemicals

S. Charles, O. Gestin, J. Bruset, D. Lamonica, V. Baudrot, A. Chaumot, O. Geffard, T. LACOUE-LABARTHE, C. Lopes

This paper presents a unified framework for solving Physiologically-Based Kinetic (PBK) models using matrix ordinary differential equations, enabling flexible modeling of chemical absorption, distribution, metabolism, and excretion across organisms.

bioRxiv · Apr 29, 2022Pharmacology & Toxicology