A Modular Framework for Multiscale Spatial Modeling of Viral Infection and Immune Response in Epithelial Tissue
T. J. Sego, J. O. Aponte-Serrano, J. Ferrari Gianlupi, S. Heaps, K. Breithaupt, L. Brusch, J. Crawshaw, J. M. Osborne, E. M. Quardokus, R. K. Plemper, J. A. Glazier
The paper introduces a modular simulation platform to model viral infection and immune response in epithelial tissue, showing that early low-dose antiviral treatment is more effective than late high-dose treatment.
PLOS Computational Biology · Dec 21, 2020Peer-reviewedBioengineering