Evaluation of SARS-CoV-2 Entry, Inflammation and New Therapeutics in Human Lung Tissue Cells
J. Grau-Exposito, D. Perea, M. Suppi, N. Massana, A. Vergara, M. J. Soler, J. Blanco, B. Trinite, J. Garcia-Perez, J. Alcami, A. Serrano-Mollar, J. Rosado, V. Falco, M. Genesca, M. J. Buzon
This paper develops a method using primary human lung tissue cells to study SARS-CoV-2 entry, inflammation, and therapeutics, identifying new drug candidates and showing interferons do not modulate ACE2 expression.
bioRxiv · Apr 21, 2021Microbiology