Human T follicular helper clones seed the germinal center-resident regulatory pool
C. Le Coz, D. A. Oldridge, R. S. Herati, N. De Luna, J. Garifallou, E. C. Cabrera, J. P. Belman, D. Pueschl, L. V. Silva, A. V. C. Knox, S. Yoon, K. B. Zur, S. D. Handler, H. Hakonarson, E. J. Wherry, , N. Romberg
The paper identifies human Tfr cells as either Treg-derived (nTfr) or Tfh-derived (iTfr) clones, with distinct functional and spatial characteristics.
bioRxiv · Oct 26, 2022Immunology