Author

J. Grootens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

G. Nilsson· 2 shared J. S. Dahlin· 2 shared J. S. Ungerstedt· 2 shared M. Ekoff· 2 shared C. Sorini· 1 shared C. Wu· 1 shared D. Boey· 1 shared E. Rönnberg· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

G. Nilsson

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2 papers

Recent·Most cited

Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors

C. Wu, D. Boey, O. Bril, J. Grootens, M. S. Vijayabaskar, C. Sorini, M. Ekoff, N. K. Wilson, J. S. Ungerstedt, G. Nilsson, J. S. Dahlin

Single-cell analysis of human hematopoiesis uncovers the stage at which FcεRI appears during mast cell differentiation and reveals disparate effects of IL-3, IL-5 and IL-33 on mast cell progenitor proliferation, survival, and suppression of FcεRI expression.

bioRxiv · Oct 1, 2021Cell Biology

Single-cell analysis reveals the KIT D816V mutation in hematopoietic stem and progenitor cells in systemic mastocytosis

J. Grootens, J. S. Ungerstedt, M. Ekoff, E. Rönnberg, M. Klimkowska, R.-M. Amini, M. Arock, S. Söderlund, M. Mattsson, G. Nilsson, J. S. Dahlin

This study identifies the KIT D816V mutation in hematopoietic stem and progenitor cells in systemic mastocytosis, showing it is present in nearly all mast cells and spans the hematopoietic lineage.

bioRxiv · Jan 22, 2019Immunology