JMJD6 participates in the maintenance of ribosomal DNA integrity in response to DNA damage
J. Fages, C. Chailleux, J. Humbert, S.-M. Jang, J. Loehr, J.-P. Lambert, C. Jacques, D. Trouche, y. canitrot
This study identifies JMJD6 as essential for rDNA stability during DNA damage by facilitating nucleolar cap formation and NBS1 recruitment, independent of rDNA transcription inhibition.
bioRxiv · Nov 6, 2019Cell Biology