Importance of AB domain in parvalbumins' calcium binding affinity
K. Immadisetty, J. Jacob-Dolan
This study investigates how the AB domain of parvalbumins affects calcium and magnesium binding affinity using molecular dynamics simulations and finds that the AB domain enhances binding efficiency through structural reorganization and helicity changes.
bioRxiv · May 27, 2022 · PreprintPhysiology