Probabilistic inference of epigenetic age acceleration from cellular dynamics
J. K. Dabrowski, E. J. Yang, S. J. C. Crofts, R. F. Hillary, D. J. Simpson, D. L. Mccartney, R. E. Marioni, E. Latorre-Crespo, T. Chandra
The paper develops a probabilistic model to infer epigenetic age acceleration from cellular dynamics, identifying acceleration and bias as measurable components linked to physiological traits and genomic loci associated with ageing.
bioRxiv · Mar 1, 2023Cell Biology