BiochemistrybioRxiv
Integrative solution structure of a PTBP1-viral IRES complex reveals strong compaction and ordering with residual conformational flexibility
G. Dorn, C. Gmeiner, T. de Vries…·F. H.- T. Allain
The paper determines the solution structure of a PTBP1-viral IRES complex using integrative modeling, revealing compaction, ordering, and residual flexibility essential for IRES-mediated translation.
DOI 10.1038/s41467-023-42012-z