Author

E. Dedic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1 Organism:yeast· 1

Frequent Co-Authors

A. Bohush· 1 shared A. Leitner· 1 shared B. P. Pedersen· 1 shared C. Gmeiner· 1 shared C. Maris· 1 shared C. P. Sarnowski· 1 shared D. L. Stokes· 1 shared E. Finol· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Bohush

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Author profile →

2 papers

Recent·Most cited

Conformational changes in the Niemann-Pick Type C1 protein NCR1 drive sterol translocation

K. M. Frain, E. Dedic, L. Nel, A. Bohush, E. Olesen, D. L. Stokes, B. P. Pedersen

This study identifies a glycocalyx in yeast vacuoles and presents cryo-EM structures of NCR1 showing conformational changes that drive sterol translocation across the glycocalyx.

bioRxiv · Sep 8, 2023Biochemistry

Integrative solution structure of a PTBP1-viral IRES complex reveals strong compaction and ordering with residual conformational flexibility

G. Dorn, C. Gmeiner, T. de Vries, E. Dedic, M. Novakovic, F. F. Damberger, C. Maris, E. Finol, C. P. Sarnowski, J. Kolhbrecher, T. J. Welsh, S. Bolisetty, R. Mezzenga, R. Aebersold, A. Leitner, , F. H.- T. Allain

The paper determines the solution structure of a PTBP1-viral IRES complex using integrative modeling, revealing compaction, ordering, and residual flexibility essential for IRES-mediated translation.

bioRxiv · Jul 8, 2022Biochemistry