The Evolution of Antibiotic Production Rate in a Spatial Model of Bacterial Competition
J. Kosakowski, P. Verma, S. Sengupta, P. G. Higgs
The paper shows that antibiotic production rate evolves to an intermediate level in a spatial model of bacterial competition, allowing coexistence of producers, non-producers, and sensitive cells, with resistant mutants coexisting under specific growth conditions.
bioRxiv · Jun 8, 2018Evolutionary Biology