The p38MAPK-MK2-HSP27 Pathway Regulates the mRNA Stability of the Senescence-Associated Secretory Phenotype
H. R. Moore, E. Alspach, J. L. Hirsch, J. Monahan, S. A. Stewart
The paper investigates how the p38MAPK-MK2-HSP27 pathway regulates mRNA stability and AUF1 occupancy in senescent cells, showing its role in promoting tumor growth through SASP factors.
bioRxiv · Jun 8, 2019 · PreprintCancer Biology