Author

E. Alspach

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. M. Highsmith· 1 shared A. S. Shavkunov· 1 shared A. Saha· 1 shared C. D. Williams· 1 shared H. R. Moore· 1 shared J. E. Pineda· 1 shared J. L. Hirsch· 1 shared J. Monahan· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. M. Highsmith

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2 papers

Recent·Most cited

Neoantigen Cancer Vaccines and Different Immune Checkpoint Therapies Each Utilize Both Converging and Distinct Mechanisms that in Combination Enable Synergistic Therapeutic Efficacy

S. Keshari, A. S. Shavkunov, Q. Miao, A. Saha, C. D. Williams, A. M. Highsmith, J. E. Pineda, E. Alspach, K. Hu, K. E. Pauken, K. Chen, M. M. Gubin

This study compares neoantigen vaccines and immune checkpoint therapies, finding they use distinct and overlapping mechanisms, with combined use showing superior efficacy.

bioRxiv · Dec 20, 2023Immunology

The p38MAPK-MK2-HSP27 Pathway Regulates the mRNA Stability of the Senescence-Associated Secretory Phenotype

H. R. Moore, E. Alspach, J. L. Hirsch, J. Monahan, S. A. Stewart

The paper investigates how the p38MAPK-MK2-HSP27 pathway regulates mRNA stability and AUF1 occupancy in senescent cells, showing its role in promoting tumor growth through SASP factors.

bioRxiv · Jun 8, 2019 · PreprintCancer Biology