Marker-based CRISPR screening reveals a MED12-p63 interaction that activates basal identity in pancreatic ductal adenocarcinoma
D. Maia-Silva, A. C. Schier, D. Skopelitis, V. Kechejian, A. Alpsoy, J. Liverpool, D. J. Taatjes, C. R. Vakoc
The paper identifies MED12-p63 interaction as a driver of basal identity in PDAC through genetic screens and biochemical analysis.
bioRxiv · Oct 24, 2023 · PreprintCancer Biology