Interplay of the Trypanosome Lytic Factor and innate immune cells in the resolution of cutaneous Leishmania infection
J. Pant, M. Samanovic, M. T. Nelson, M. K. Keceli, J. Verdi, S. M. Beverley, J. Raper
This paper investigates how Trypanosome Lytic Factor (TLF) and neutrophils interact to reduce Leishmania major infection, showing TLF requires acidic phagosomes and surface glycoconjugates for parasite lysis.
bioRxiv · Jul 2, 2020Microbiology